People

Theoretical ecology, disease ecology, population dynamics, and systems biology.

Research in my group is entirely theoretical/computational in nature.

Our present research interests are in two areas: (i) nucleoside material chemistry (synthesis, characterization of interactions); and (ii

Roles of metals in metalloenzymes; microbial iron acquisition, including siderophores and new metallo-enzymes.

The Carlini Group focuses on breaking down barriers between endogenous biochemical signals and exogenous soft materials for the fabrication of smart devices.

Human stem cell research; Molecular mechanisms of stem cell differentiation; Derivation of ocular cells from stem cells; Soft tissue regeneration.

Biochemistry; protein structure and function relationships; protein dynamics; chemotaxis in bacteria.

The genome within all cells of a multicellular organism is identical, yet different cells within the heart, brain or small intestine for

Experimental Soft Matter and Biological Physics

Physical foundations of macromolecular technology: self-assembly, polymer mechanics and stability, energy transport, diffusion, and DNA-based nanotechnology.

In the Gardner Lab, we focus on how the cell has solved challenges for a metabolic organelle, the peroxisome.

Addition of small molecules, such as an alcohol or an osmolyte, to aqueous solutions of peptides and proteins often alters the dominant c

The role of radicals in enzyme catalysis and degradation, development of electron bifurcating flavoproteins, and biogeochemical redox cycling of phosphorus.

Nature has evolved the capacity to carry out many challenging chemical transformations of great interest to synthetic chemistry if they c

Molecular mechanisms of ribosome pausing during protein synthesis and recruitment of SsrA (tmRNA) to stalled ribosomes.

RNA folding and evolution; nucleic acid-based bionanotechnology and biomaterials; emergence of complexity in living systems.

My lab is interested in understanding the brain-wide, multi-sensory information processing and integration that underlies how the brain enables navigational decisions.

Prof Kodio studies the patterns in soft matter and fluids mechanics.

Basic mechanisms and disorders of neural plasticity; the role of microRNAs in stem cell differentiation.

Molecular mechanisms of Alzheimer's disease; structure/function studies on tau using NMR, spectroscopic, biochemical, molecular, and cell biological methods; role of cdk5/p35 in neuronal development and signal transduction.

Combining theory and experimentation to understand how navigational decisions come about in terms of neural-circuit computation.

Cellular communication between bacteria, including mechanisms and biology of contact-dependent growth inhibition; epigenetic gene regulatory mechanisms.

Microbial pathogenesis; innate and adaptive immune responses to infection; coagulopathy and inflammation of sepsis; vaccine development.

Soft Matter Theory and Biological Physics

The mosquito, Aedes aegypti, spreads the viruses that cause dengue, yellow fever, zika and other diseases that affects hundreds of millio

Every day, every single one of the trillions of cells in the human body makes an active decision whether to live or die.

We use high resolution live imaging, synthetic biology and biochemistry to figure out when and where signaling molecules are activated to make these essential decisions. We are motivated by re-wiring macrophage signaling pathways to generate new cancer immunotherapies.

Bio-nano technology including molecular mechanisms controlling self assembly, emergent properties of biomolecular systems from minerals to dynamically tunable color in octopus skin; translation to revolutionary new routes to semiconductors, optoelectronics and energy.

The Mukherjee group will pursue fundamental advances at the intersection of molecular biology, biomedical imaging, and biophysics.  

Aquatic Biology, Behavior, Ecological and Evolutionary Physiology, Evolution, Evolutionary Ecology, Evolutionary Genetics, Macroevolution, Marine Biology, Organismal Biology, Zoology

Neurotransmitter storage; transporter structure and function; development of in vivo diagnostics for PET and SPECT, rapid assays for drug abuse.

Soft condensed matter theory including biopolymer and biomembrane electrostatics, protein-membrane interactions, biopolymer solutions, and solution properties of conjugated polymers.

Bioengineering and protein biophysics.

Drug development. Nanoparticle-based delivery of siRNA, proteins, and drugs into cells (cancer/embryonic stem cell). Laser-dependent spatio-temporal control of drug targeting.
    

Human cells constantly repair DNA damage caused by everything from biological processes and chemical insults to CRISPR-Cas9 gene editing reagents.

When a fertilized egg is transformed into a complex multicellular animal, how do cells learn when to divide, differentiate or die at the

Structures and interactions in complex fluids and biological systems; new materials for gene delivery into mammalian cells.

The Saleh Group studies the physics of soft matter systems, with a focus on the active and passive micro-mechanics of biomolecules and polymers.

Molecular biology of animal virus-cell interactions; antiviral innate immunity & mechanisms of interferon action; translational control of gene expression in mammalian cells; and A-to-I RNA editing

Bioelectronics, Single entity Biophysics, Nano-electrochemistry, Electron Transfer, Enzyme Catalysis

Research in the Shea group focuses on developing and applying the techniques of statistical and computational physics to the study of bio

Quantitative systems biology and bioinformatics; statistical mechanics of non-equilibrium systems.

Genetics, Neural Circuits, and Motor sequences.

Analysis of biological data including sequences, structures, and images; synthesis and analysis of biological networks.

Vertebrate developmental biology; growth factors and axis specification in Xenopus.

Properties of the biopolymer scaffolding that surrounds cells in the body, known as the extracellular matrix, are known to influence many

We use ideas and concepts from physics, computer science, and mathematics to ask how embryos get in shape, and how organs function. 

Design, synthesis, and characterization of new bioinorganic materials with an emphasis on understanding interface assembly & control of bioprocesses.

Ion channels in the nervous system and cardiac muscle; molecular mechanisms of ion channel trafficking, regulation, and signal transduction.

Dr. Volkmann’s research focuses on the development and application of innovative new computational, artificial intelligence, and data science tools to bridge information between the atomic and cellular scales

Biochemistry and biophysics of bio-adhesion in marine organisms; bio and nanomechanics of sclerotized composites; liquid crystals and molecular gradients in biomolecular materials.

The Weimbs Lab is centered around two related areas of investigation:  Autosomal-dominant polycystic kidney disease and SNAREs and epithelial cell polarity.

The Wilson Lab comines tools from Biology, Engineering, and Physics to understand the cell's perceptual field.  

Biochemistry and function of cytoskeletal proteins; regulation of microtubules assembly and dynamics.

The Yang laboratory devises novel biocatalytic and protein engineering strategies to tackle challenging problems in synthetic organic che